La Roche-Posay Retinol B3 Serum is an anti-aging face and neck serum that combines pure retinol and vitamin B3 to reduce the appearance of lines, wrinkles and sun damage. This dermatologically-tested formula is suitable for sensitive skin while providing optimal effectiveness. The serum should be applied in the evening by filling the dropper with 3-4 drops and gently spreading on cleansed face and neck, followed by moisturizer. For best results, always apply sunscreen the following day. The pure retinol may turn slightly yellow when exposed to air, but this does not affect its efficacy or tolerance. The formula features a gradual-release retinol system for enhanced effectiveness while maintaining skin comfort.